Can ChatGPT Diagnose Alzheimer's Disease?
Journal:
arXiv
Published Date:
Feb 10, 2025
Abstract
Can ChatGPT diagnose Alzheimer's Disease (AD)? AD is a devastating
neurodegenerative condition that affects approximately 1 in 9 individuals aged
65 and older, profoundly impairing memory and cognitive function. This paper
utilises 9300 electronic health records (EHRs) with data from Magnetic
Resonance Imaging (MRI) and cognitive tests to address an intriguing question:
As a general-purpose task solver, can ChatGPT accurately detect AD using EHRs?
We present an in-depth evaluation of ChatGPT using a black-box approach with
zero-shot and multi-shot methods. This study unlocks ChatGPT's capability to
analyse MRI and cognitive test results, as well as its potential as a
diagnostic tool for AD. By automating aspects of the diagnostic process, this
research opens a transformative approach for the healthcare system,
particularly in addressing disparities in resource-limited regions where AD
specialists are scarce. Hence, it offers a foundation for a promising method
for early detection, supporting individuals with timely interventions, which is
paramount for Quality of Life (QoL).
