SimICD: A Closed-Loop Simulation Framework For ICD Therapy
Journal:
arXiv
Published Date:
May 2, 2025
Abstract
Virtual studies of ICD behaviour are crucial for testing device functionality
in a controlled environment prior to clinical application. Although previous
works have shown the viability of using in silico testing for diagnosis, there
is a notable gap in available models that can simulate therapy progression
decisions during arrhythmic episodes. This work introduces SimICD, a simulation
tool which combines virtual ICD logic algorithms with cardiac electrophysiology
simulations in a feedback loop, allowing the progression of ICD therapy
protocols to be simulated for a range of tachy-arrhythmia episodes. Using a
cohort of virtual patients, we demonstrate the ability of SimICD to simulate
realistic cardiac signals and ICD responses that align with the logic of
real-world devices, facilitating the reprogramming of ICD parameters to adapt
to specific episodes.
