A Japanese Language Model and Three New Evaluation Benchmarks for Pharmaceutical NLP
Journal:
arXiv
Published Date:
May 22, 2025
Abstract
We present a Japanese domain-specific language model for the pharmaceutical
field, developed through continual pretraining on 2 billion Japanese
pharmaceutical tokens and 8 billion English biomedical tokens. To enable
rigorous evaluation, we introduce three new benchmarks: YakugakuQA, based on
national pharmacist licensing exams; NayoseQA, which tests cross-lingual
synonym and terminology normalization; and SogoCheck, a novel task designed to
assess consistency reasoning between paired statements. We evaluate our model
against both open-source medical LLMs and commercial models, including GPT-4o.
Results show that our domain-specific model outperforms existing open models
and achieves competitive performance with commercial ones, particularly on
terminology-heavy and knowledge-based tasks. Interestingly, even GPT-4o
performs poorly on SogoCheck, suggesting that cross-sentence consistency
reasoning remains an open challenge. Our benchmark suite offers a broader
diagnostic lens for pharmaceutical NLP, covering factual recall, lexical
variation, and logical consistency. This work demonstrates the feasibility of
building practical, secure, and cost-effective language models for Japanese
domain-specific applications, and provides reusable evaluation resources for
future research in pharmaceutical and healthcare NLP. Our model, codes, and
datasets are released at https://github.com/EQUES-Inc/pharma-LLM-eval.