CoxNTF: A New Approach for Joint Clustering and Prediction in Survival Analysis
Journal:
arXiv
Published Date:
Jun 6, 2025
Abstract
The interpretation of the results of survival analysis often benefits from
latent factor representations of baseline covariates. However, existing
methods, such as Nonnegative Matrix Factorization (NMF), do not incorporate
survival information, limiting their predictive power. We present CoxNTF, a
novel approach that uses non-negative tensor factorization (NTF) to derive
meaningful latent representations that are closely associated with survival
outcomes. CoxNTF constructs a weighted covariate tensor in which survival
probabilities derived from the Coxnet model are used to guide the tensorization
process. Our results show that CoxNTF achieves survival prediction performance
comparable to using Coxnet with the original covariates, while providing a
structured and interpretable clustering framework. In addition, the new
approach effectively handles feature redundancy, making it a powerful tool for
joint clustering and prediction in survival analysis.