Artificial Intelligence in Reminiscence Therapy for Older Adults: A Systematic Review Protocol

The global aging population faces increasing challenges related to cognitive decline, social isolation, and psychological well-being. Reminiscence therapy has emerged as an effective non-pharmacological intervention, and recent advances in artificial intelligence offer opportunities to enhance these therapeutic approaches. To systematically review and synthesize evidence on the integration of artificial intelligence technologies in reminiscence therapy for aging populations, examining effectiveness, acceptability, implementation factors, and ethical considerations. This protocol follows PRISMA-P guidelines and employs the PICOS framework. Comprehensive searches will be conducted in PubMed, Web of Science, Embase, CINAHL, MEDLINE, The Cochrane Library, PsycINFO, and Scopus from inception to October 2025. Studies examining AI-enhanced reminiscence therapy in adults aged 60 years and above will be included. Two independent reviewers will screen studies using Covidence, extract data, and assess quality using appropriate risk of bias tools. Data synthesis will involve meta-analysis where appropriate or narrative synthesis following SWiM guidelines. This protocol establishes a rigorous methodology for examining an emerging field at the intersection of gerontology and artificial intelligence. The systematic approach will provide evidence-based insights for clinical practice, technology development, and policy-making while identifying research gaps and ethical considerations in AI-enhanced therapeutic interventions for older adults.