Curcumin Aattenuates the Expression of Metalloprotease (AHA_0978) and Serine Protease (AHA_3857) Genes in Aeromonas Hydrophila.

Journal: Galen medical journal
Published Date: Dec 17, 2023

Abstract

BACKGROUND: Aeromonas hydrophila is a pathogenic bacterium responsible for various infections in humans and animals. Bacterial exoproteases are considered an important determinant in the pathogenicity of A. hydrophila. Serine protease and metalloprotease, that are regulated by the bacterial Quorum sensing (QS) system are important virulent factors in the pathogenicity of A. hydrophila. Anti-QS potential of curcumin has been reported, previously. In this work, we characterized the effect of curcumin on the expression of the metalloprotease and serine protease genes in A. hydrophila.

Authors

  • Mahdieh SobhZahedi
    Department of Biology, Faculty of Science, University of Guilan, Rasht, Iran.
  • Hojjatollah Zamani
    Department of Biology, Faculty of Science, University of Guilan, Rasht, Iran.
  • Mohammad Hossein YektaKooshali
    Razi Hospital, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran.

Keywords

No keywords available for this article.

External Resources

Popular Topics
Recent Journals