Safety and Efficacy of Tranexamic Acid in Spinal Surgery: A Systematic Review and Meta-Analysis.

Journal: Spine surgery and related research
Published Date: Dec 27, 2023

Abstract

BACKGROUND: Tranexamic acid (TXA) has gained popularity in spinal surgery because of its potential to reduce blood loss. However, concerns regarding its safety and efficacy remain. This systematic review and meta-analysis aimed to evaluate the efficacy of TXA in reducing blood loss and its safety profile in spinal surgeries.

Authors

  • Kento Yamanouchi
    Department of Orthopaedic Surgery, School of Medicine, International University of Health and Welfare, Narita, Japan.
  • Haruki Funao
    Department of Orthopaedic Surgery, School of Medicine, International University of Health and Welfare, Narita, Japan.
  • Naruhito Fujita
    Department of Orthopaedic Surgery, School of Medicine, International University of Health and Welfare, Narita, Japan.
  • Shigeto Ebata
    Department of Orthopaedic Surgery, School of Medicine, International University of Health and Welfare, Narita, Japan.
  • Mitsuru Yagi
    Department of Orthopaedic Surgery, School of Medicine, International University of Health and Welfare, Narita, Japan.

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