Lightweight Seizure Prediction Model based on Kernel-Enhanced Global Temporal Attention.

Clinically, epilepsy manifests as a chronic condition marked by unprovoked, recurrent seizures, plaguing over 70 million individuals with debilitating seizures and life-threatening complications. Approximately 30% of patients with epilepsy do not respond to conventional antiepileptic drugs, indicating the limited efficacy of these medications in controlling seizures universally. Therefore, seizure prediction has become a key factor in enabling timely intervention for epilepsy patients, which can provide crucial time for clinical treatment and preventive measures. This study aimed to propose a lightweight seizure prediction model integrating a residual network (ResNet) with a kernel-enhanced global temporal attention Block (GTA Block). The ResNet extracts electroencephalogram (EEG) features while maintaining gradient stability, and the GTA mechanism constructs full-sequence temporal association matrices to capture the dynamic evolution of EEG patterns. Then a kernel function is embedded into GTA Block for mapping EEG samples into a high-dimensional space in which the distinction between preictal and interictal states is enhanced. The model significantly outperforms existing methods while maintaining a lightweight architecture suitable for embedded systems. With only 1.94 million parameters and an inference time of 0.00207[Formula: see text]s, this lightweight design facilitates real-time deployment on wearable devices, enhancing feasibility for continuous clinical monitoring in resource-constrained settings.