Ethical challenges in kidney transplantation.

Journal: Current opinion in nephrology and hypertension
Published Date: Nov 27, 2025

Abstract

PURPOSE OF REVIEW: This review provides a comprehensive examination of the current inequities and ethical challenges in kidney transplantation and highlights some of the most urgent issues related to organ allocation and emerging technologies. RECENT FINDINGS: Several recent news and media reports have significantly undermined public trust in the organ transplantation and allocation process. This review discusses some of these controversies and proposes strategies to restore confidence in the system. With advancements in gene editing, xenotransplantation is becoming a tangible reality, bringing forth new ethical challenges explored in this paper. Likewise, as artificial intelligence continues to permeate medicine and moves closer to integration within transplantation, proactive preparation and ethical foresight are essential. SUMMARY: In conclusion, we aim to draw attention to pressing ethical dilemmas in kidney transplantation and suggest actionable steps to restore trust.

Authors

  • Avantika Israni
    Nephrology Division, Department of Medicine, University of Arkansas for Medical Sciences, Little Rock, Arkansas.
  • Abhishek Israni
  • Judith Benstein
    Nephrology Division, Department of Medicine, New York University Grossman School of Medicine, New York, New York, USA.

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