Organoid intelligence: Integration of organoid technology and artificial intelligence in the new era of in vitro models.

Journal: Medicine in novel technology and devices
Published Date: Nov 27, 2023

Abstract

Organoid Intelligence ushers in a new era by seamlessly integrating cutting-edge organoid technology with the power of artificial intelligence. Organoids, three-dimensional miniature organ-like structures cultivated from stem cells, offer an unparalleled opportunity to simulate complex human organ systems in vitro. Through the convergence of organoid technology and AI, researchers gain the means to accelerate discoveries and insights across various disciplines. Artificial intelligence algorithms enable the comprehensive analysis of intricate organoid behaviors, intricate cellular interactions, and dynamic responses to stimuli. This synergy empowers the development of predictive models, precise disease simulations, and personalized medicine approaches, revolutionizing our understanding of human development, disease mechanisms, and therapeutic interventions. Organoid Intelligence holds the promise of reshaping how we perceive in vitro modeling, propelling us toward a future where these advanced systems play a pivotal role in biomedical research and drug development.

Authors

  • Huaiyu Shi
    Department of Biomedical & Chemical Engineering, Syracuse University, Syracuse, NY, USA.
  • Andrew Kowalczewski
    Department of Biomedical & Chemical Engineering, Syracuse University, Syracuse, NY, USA.
  • Danny Vu
    Department of Biomedical & Chemical Engineering, Syracuse University, Syracuse, NY, USA.
  • Xiyuan Liu
    Department of Mechanical & Aerospace Engineering, Syracuse University, Syracuse, NY, USA.
  • Asif Salekin
    Department of Electrical Engineering & Computer Science, Syracuse University, Syracuse, NY, USA.
  • Huaxiao Yang
    Department of Biomedical Engineering, University of North Texas, Denton, TX, USA.
  • Zhen Ma
    Department of Biomedical & Chemical Engineering, Syracuse University, Syracuse, NY, USA.

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