The Role of Vitamin D Binding Protein and Vitamin D Level in Mortality of Sepsis Patients.

Journal: Reports of biochemistry & molecular biology
Published Date: Oct 1, 2023

Abstract

BACKGROUND: Vitamin D plays crucial roles in immune cell function, including macrophage activation, immune response modulation, and antimicrobial peptide production. Low vitamin D levels can result in reduced immune response, heightened inflammation, and impaired organ function, thereby exacerbating sepsis severity and impacting patient prognosis. This study investigates the influence of vitamin D binding protein expression and vitamin D levels on the mortality of septic patients.

Authors

  • Liliriawati Ananta Kahar
    Department of Anesthesiology and Intensive Care, Faculty of Medicine, Andalas University, Dr. M. Djamil General Hospital, Padang, 25171, Indonesia.
  • Yusrawati Yusrawati
    Department of Obstetrics and Gynecology, Faculty of Medicine, Andalas University, Padang, 25171, Indonesia.
  • Jamsari Jamsari
    Department of Biotechnology, Postgraduate Program, Andalas University, Padang, 25163, Indonesia.
  • Tinni Maskoen
    Faculty of Medicine, Padjadjaran University, Bandung, 45363, Indonesia.
  • Kornelis Aribowo
    Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Andalas University, Padang, 25171, Indonesia.
  • Wiwi Monika Sari
    Intensive Care Unit, Dr. M. Djamil General Hospital, Padang, 25171, Indonesia.

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