Effect of amoxicillin and clindamycin on the gene expression of markers involved in osteoblast physiology.

Journal: Journal of dental sciences
Published Date: Jul 18, 2023

Abstract

BACKGROUND/PURPOSE: Amoxicillin and clindamycin are the most effective decontaminants for intraoral bone grafts before their application in bone regeneration without cytotoxic effects on osteoblasts, but their effects on the gene expression of markers involved in osteoblast growth and differentiation remain unclear. The study objective was to determine the effects of amoxicillin and clindamycin on the gene expression of markers involved in osteoblast growth and differentiation.

Authors

  • Francisco Javier Manzano-Moreno
    Biomedical Group (BIO277), Department of Stomatology, School of Dentistry, University of Granada, Granada, Spain.
  • Anabel Gónzalez-Acedo
    Instituto Investigación Biosanitaria, ibs.Granada, Spain.
  • Elvira de Luna-Bertos
    Instituto Investigación Biosanitaria, ibs.Granada, Spain.
  • Enrique García-Recio
    Instituto Investigación Biosanitaria, ibs.Granada, Spain.
  • Concepción Ruiz
    Instituto Investigación Biosanitaria, ibs.Granada, Spain.
  • Candela Reyes-Botella
    Biomedical Group (BIO277), Department of Stomatology, School of Dentistry, University of Granada, Granada, Spain.

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