Prostate Cancer Screening in the MR Imaging Era: Evidence, Strategies, and Future Directions.

Prostate cancer screening has entered a new era with the integration of MR imaging and artificial intelligence (AI) into diagnostic workflows. This paradigm shift allows for the more accurate identification of clinically significant prostate cancer while reducing the overdiagnosis of low-grade disease. AI-driven image reconstruction and lesion detection platforms are improving diagnostic accuracy and access. This article synthesizes recent advances in MR imaging-based prostate cancer screening, focusing on the evidence for its utility, risk-adjusted screening strategies, emerging AI applications, and future directions aimed at increasing precision, efficiency, and equity in prostate cancer care.