Protective Effect of Baclofen on Ovarian Cystogenesis and Morphine-Induced Lipid Profile Change in Female Rats.

Journal: Indian journal of endocrinology and metabolism
Published Date: Jun 30, 2023

Abstract

INTRODUCTION: Morphine induces ovarian cysts that cause obesity and disrupt sex hormone secretion. Baclofen, a gamma-aminobutyric acid receptor agonist, can help regulate sex hormones and reduce harmful blood lipids by protecting against morphine-induced gamma-aminobutyric acid inhibition. We investigated the prophylactic effect of baclofen in rats receiving morphine by comparing with the untreated groups.

Authors

  • Zahra Jamshidi
    Department of Biology, Shahed University, Tehran, Iran.
  • Manizheh Karami
    Department of Biology, Shahed University, Tehran, Iran.
  • Mohsen Khalili
    Department of Physiology, Shahed University, Tehran, Iran.
  • Mehrdad Roghani
    Department of Physiology, Shahed University, Tehran, Iran.

Keywords

No keywords available for this article.

External Resources

Popular Topics
Recent Journals