Venture Capital Investments in Radiology From 2000 to 2023.

OBJECTIVE: Venture capital (VC) is playing a growing role in driving innovation in health care. Although previous studies have examined VC trends in various medical fields, limited research has focused on investment patterns in radiology. This study aimed to assess VC investment trends in radiology-focused companies from 2000 to 2023 and to identify key areas of innovation. METHODS: A retrospective analysis of VC investments in radiology companies from 2000 to 2023 was conducted using the PitchBook database (PitchBook Data, Inc, Seattle, Washington). Companies were categorized into medical devices, health care services, artificial intelligence (AI) health care software, non-AI health care software, consumer goods, and biotechnology and drug discovery. Total capital investment, number of funded companies, clinical trials, and international patent filings were assessed. In addition, the associations of capital investment with patent and clinical trial activity, both used as proxies for innovation, were analyzed using Spearman's ρ. RESULTS: Between 2000 and 2023, 2,851 VC firms made 2,584 investments in 646 radiology companies, totaling $11.4 billion. Investment activity peaked in 2021 with $2.18 billion. The most funded categories were medical devices ($3.21 billion), AI health care software ($2.54 billion), and biotechnology ($2.08 billion). These companies were associated with a total of 267 clinical trials and 9,224 patents, with medical devices and AI health care software leading in innovation, accounting for 5,465 (59.2%) and 1,220 (13.2%) patents, respectively. CONCLUSION: VC investment in radiology has grown considerably over the past two decades, particularly in health care software and medical devices. This trend underscores the increasing role of private capital in shaping innovation within radiology.