Large language models in radiology exams: A cross-sectional comparative analysis of performance in Turkish and English.

Journal: Medicine
Published Date:

Abstract

This study evaluated the success of large language models on radiology questions, analyzing language variations, temporal consistency, and performance against residents. We evaluated ChatGPT-5, Grok-4, Claude 4.5 Sonnet, and Gemini 2.5 Pro using 100 multiple-choice questions across 5 subspecialties. Linguistic impact (Turkish vs English) and 1-week temporal reliability were assessed. Performance was benchmarked against a control group of 18 radiology residents (years 1-3). Gemini 2.5 Pro achieved the highest accuracy (90%), followed by Claude 4.5 Sonnet (86%). All models and 3rd-year residents significantly outperformed junior residents. While no significant performance gap existed between languages (P = 1.000), Claude 4.5 Sonnet demonstrated superior temporal reliability (κ = 0.872) compared with the moderate consistency of Grok-4 and ChatGPT-5. High-performance large language models provide accurate radiology knowledge comparable with senior residents, showing significant potential for education. Future research must incorporate image-based datasets to determine clinical efficacy.

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