Three-Dimensional Fractal Analysis of the Interstitial Cells of Cajal Networks of Gastrointestinal Tissue Specimens.

Journal: Cellular and molecular bioengineering
Published Date: Nov 27, 2023

Abstract

INTRODUCTION: Several functional gastrointestinal disorders (FGIDs) have been associated with the degradation or remodeling of the network of interstitial cells of Cajal (ICC). Introducing fractal analysis to the field of gastroenterology as a promising data analytics approach to extract key structural characteristics that may provide insightful features for machine learning applications in disease diagnostics. Fractal geometry has advantages over several physically based parameters (or classical metrics) for analysis of intricate and complex microstructures that could be applied to ICC networks.

Authors

  • Sue Ann Mah
    Auckland Bioengineering Institute, The University of Auckland, Auckland, New Zealand.
  • Recep Avci
    Auckland Bioengineering Institute, The University of Auckland, Auckland, New Zealand.
  • Jean-Marie Vanderwinden
    Laboratoire de Neurophysiologie, Faculté de Médecine, Université Libre de Bruxelles, Brussels, Belgium.
  • Peng Du
    Auckland Bioengineering Institute, The University of Auckland, Auckland, New Zealand.

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