Multi-parameter scoliosis evaluation from dual-view x-rays via a local sine-based projection model.

Journal: Physics in medicine and biology
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Abstract

OBJECTIVE: To develop a robust and accurate multi-parameter assessment framework for adolescent idiopathic scoliosis (AIS) based on spinal X-ray images, overcoming the limitations of traditional Cobb angle-based evaluation. APPROACH: We proposed a dual-view labeling protocol and employed a Residual U-Net architecture to segment vertebral bodies in 700 paired anteroposterior and lateral X-rays. A novel Local Sine-based Spinal Projection Model (LS-SPM) was introduced to calculate vertebral inclination angles and derive consecutive Cobb angles. Additional spinal parameters, including coronal balance (T1PL-CSVL), force line (FL), and force line balance (FLB), were computed to enable comprehensive spinal evaluation. MAIN RESULTS: The proposed method achieved a vertebral segmentation Dice coefficient of 94.7%. The mean absolute error of the Cobb angle was 2.71°, outperforming the minimum bounding rectangle method (3.46°) and novice manual measurements (5.40°), with an intraclass correlation coefficient of 0.958. In diagnostic grading, 120 out of 142 patients were correctly classified (84.5% success rate). Longitudinal follow-up demonstrated accurate tracking of structural improvements and coronal balance recovery following conservative treatment. SIGNIFICANCE: This approach enables automatic, precise, and comprehensive scoliosis evaluation by integrating fine-grained segmentation with geometric modeling of spinal curvature. The proposed method improves spinal assessment accuracy and facilitates longitudinal scoliosis monitoring, offering substantial clinical utility and impact in computer-aided orthopedic diagnosis.

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