Circulating Plasma Exosomal PD-L1 Predicts Prognosis of Head and Neck Squamous Cell Carcinoma After Radiation Therapy.

Journal: Advances in radiation oncology
Published Date: Aug 15, 2023

Abstract

PURPOSE: Radiation therapy is widely used to treat head and neck squamous cell carcinoma (HNSCC). This study evaluated the association between circulating plasma programmed death-ligand 1 (PD-L1) and the outcomes of patients with HNSCC after radiation therapy.

Authors

  • Keisuke Tamari
    Department of Radiation Oncology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
  • Kazumasa Minami
    Department of Medical Physics and Engineering, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
  • Shotaro Tatekawa
    Department of Radiation Oncology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
  • Yuji Seo
    Department of Carbon Ion Radiotherapy, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
  • Takahito Fukusumi
    Department of Otorhinolaryngology-Head and Neck Surgery, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
  • Hidenori Tanaka
    Department of Otorhinolaryngology-Head and Neck Surgery, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
  • Motoyuki Suzuki
    Department of Otorhinolaryngology-Head and Neck Surgery, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
  • Hirotaka Eguchi
    Department of Otorhinolaryngology-Head and Neck Surgery, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
  • Yukinori Takenaka
    Department of Otorhinolaryngology-Head and Neck Surgery, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
  • Takero Hirata
    Department of Radiation Oncology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
  • Kazuhiko Hayashi
    Department of Radiation Oncology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
  • Fumiaki Isohashi
    Department of Radiation Oncology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
  • Shinichi Shimizu
    Department of Carbon Ion Radiotherapy, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
  • Masahiko Koizumi
    Department of Medical Physics and Engineering, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
  • Hidenori Inohara
    Department of Otorhinolaryngology-Head and Neck Surgery, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
  • Kazuhiko Ogawa
    Department of Radiation Oncology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.

Keywords

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