Wellens' Sign and Syndrome Detected With the Home Use of a Novel 12-Lead Electrocardiogram.
Journal:
JACC. Case reports
Published Date:
Jul 29, 2026
Abstract
BACKGROUND: Wellens' sign is a high-risk electrocardiogram (ECG) pattern associated with proximal left anterior descending artery stenoses and high risk of major adverse cardiovascular events. EARLY REPORTS SUMMARY: A man with transient chest pain remained asymptomatic including with exertion for 48 hours. His friend performs a home 12-lead ECG using a novel, artificial intelligence-enabled device that showed a classic Wellens' Sign Type A, and the man went to a hospital and subsequently received 2 stents in his proximal left anterior descending artery. DISCUSSION: The Kardia12L is a Food and Drug Administration-cleared, pocket-sized ECG device that generates an interpreted 12-lead ECG. Devices like Kardia 12L can lead to diagnosis of cardiovascular disease from home and improve outcomes. NOVELTY: This case highlights the utilization of novel technology to facilitate accurate diagnosis. TAKE-HOME MESSAGES: This case illustrates Wellens' Type A Sign and Syndrome in an asymptomatic patient with a history of chest pain. New technology enables the recording of a diagnostic ECG in high-risk patients anywhere.
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