A Comprehensive Database of Simulations and Meshes of Coronary Arteries from the Fame 2 Trial
Journal:
bioRxiv
Published Date:
Aug 5, 2026
Abstract
In this work, we publish the 3D unsteady Navier-Stokes numerical simulations and meshes of coronary arteries reconstructed from invasive X-ray coronary angiograms acquired during in the Fractional Flow Reserve versus Angiography for Multivessel Evaluation 2 (FAME 2) trial. Out of the 914 clinical images, 779 vessels are successfully reconstructed and meshed. The remaining 135 vessels have been discarded since they exhibited self-intersecting geometry during the reconstruction process. The meshes are hexahedral and all of them have the same number of vertices and identical connectivity; their high quality is demonstrated using standard mesh quality indices. The simulations are performed using the Finite Element Method (FEM) with state-of-the-art coronary boundary conditions applied at the outlet. The motivation behind this effort relies from the scarcity of publicly available numerical haemodynamics data, despite the growing interest in data-driven modeling and machine learning techniques. The database is available at the link: https://doi.org/10.7910/DVN/GPCUNS
