Evaluation of e-health interventions to strengthen nursing care in the neonatal intensive care unit: A systematic review.

PURPOSE: This review explores how e-health interventions are utilized within neonatal intensive care units to support nursing practice, with particular attention to their implementation areas, influence on care outcomes, and overall value for nursing services. METHODS: Following PRISMA 2020 guidelines, 24 eligible studies were identified through a systematic search of four databases and appraised using design-specific quality assessment tools. RESULTS: The review synthesized findings from 24 studies investigating the integration of e-health technologies into neonatal nursing care. The evidence, spanning publications from 2000 to 2026, encompassed telehealth, mobile health applications, clinical decision support tools, digital learning strategies, and artificial intelligence-enabled systems. These interventions were mainly designed to enhance family participation, support care transitions following discharge, support breastfeeding, improve patient safety, and assist clinical decision-making processes. Overall, the findings suggest that e-health technologies contribute positively to several dimensions of neonatal care, particularly parental involvement, continuity of care, and breastfeeding support. Furthermore, emerging digital education and artificial intelligence applications appear promising for advancing nursing care delivery. Quality appraisal findings indicated a predominantly high-quality evidence base. CONCLUSION: E-health interventions can support family-centered care, continuity of care, patient safety, and clinical decision-making in neonatal intensive care units. Further high-quality multicenter studies are needed to evaluate their impact on clinical and nursing outcomes. CLINICAL IMPLICATIONS: The integration of e-health technologies into neonatal intensive care practice may enhance care delivery and support family engagement.