ProLego: tool for extracting and visualizing topological modules in protein structures.

Journal: BMC bioinformatics
Published Date:

Abstract

BACKGROUND: In protein design, correct use of topology is among the initial and most critical feature. Meticulous selection of backbone topology aids in drastically reducing the structure search space. With ProLego, we present a server application to explore the component aspect of protein structures and provide an intuitive and efficient way to scan the protein topology space.

Authors

  • Taushif Khan
    Interuniversity Institute of Bioinformatics in Brussels, ULB-VUB, La Plaine Campus, Triomflaan.
  • Shailesh Kumar Panday
    School of Computational and Integrative Sciences, Jawaharlal Nehru University, New Delhi, 110067, India.
  • Indira Ghosh
    School of Computational and Integrative Sciences, Jawaharlal Nehru University, New Delhi, 110067, India.