Human or AI-generated voiceover for chemotherapy education video? Evidence from knowledge and practice tests improvement among cancer patients by pharmacists.

BackgroundEducational videos play a crucial role in enhancing healthcare delivery. Developing an educational video designed to improve patient understanding of catastrophic treatment. During the video's creation, two voiceover methods were employed: human voices and artificial intelligence (AI)-generated voices. To date, the impact of voice-over origin-whether human or AI-on patient knowledge acquisition remains unexplored and warrants further investigation. This study aimed to assess the differences in knowledge and practice scores among cancer patients exposed to educational video materials about chemotherapy, comparing human voice with AI-generated voice narrations.MethodsA total of 129 cancer patients participated in this study. Designed as a case-control study, participants were divided into three groups: a control group, a group receiving videos with human voice narrations, and a group receiving videos with AI-generated voice narrations. All participants completed a questionnaire assessing their understanding of chemotherapy. A three-group quantitative comparative analysis was conducted, focusing on topics such as administration procedures, treatment goals, and the management of adverse drug reactions.Key findingsBoth educational videos with human- and AI-generated voiceovers should be incorporated into the oncology healthcare system due to their effectiveness in improving understanding of treatment. Notably, educational videos featuring human-voice narration consistently enrich knowledge and attitude scores among cancer patients across all assessed chemotherapy topics.ConclusionThe educational videos, whether in human or AI voices, were effective in increasing cancer patients' knowledge and attitudes across all key topics. There was a sustained trend toward human-voice videos in knowledge and attitudes among cancer patients; therefore, the human educational video showed significant improvement in understanding of chemotherapy administration, goals, and adverse drug reactions. Although there was no difference between human and AI voice education, trends toward combining human voice with realistic scenario videos should be considered to facilitate deeper patient understanding.