Clinical applications of remote patient monitoring.

Remote patient monitoring (RPM) utilizes a variety of technologies that enable rapid transmission of health data, allowing healthcare providers to manage medical conditions outside the hospital setting. As an increasingly important component of pediatric telehealth and healthcare delivery, RPM has been successfully implemented across multiple specialties. This review highlights RPM programs at the Children's Hospital of Philadelphia (CHOP), including initiatives in cardiology, neonatology, primary care, gastrostomy tube care, and neurology. These programs have demonstrated success in reducing unnecessary hospitalizations and emergency department visits, increasing access to care and subspecialty follow-up, and lowering mortality among children with chronic diseases. The review also examines the digital health technologies that support these programs. In addition, artificial intelligence is playing an expanding role in RPM through predictive alerts, risk stratification, and agentic monitoring tools that enable more personalized and proactive care. Despite these benefits, important challenges remain, including disparities in digital literacy, language barriers, and licensing restrictions. We propose that a hybrid care model integrating RPM, digital health technologies, and in-person visits provides a comprehensive framework for pediatric healthcare delivery. As RPM continues to expand across pediatric subspecialties, the development of telehealth "neighborhoods" may help strengthen medical homes for children with complex chronic conditions. Such models have the potential to improve clinical outcomes, enhance care coordination, and reduce healthcare disparities among vulnerable pediatric populations.