Whole blood RNA sequencing identifies transcriptional differences between primary sclerosing cholangitis and ulcerative colitis.

Journal: JHEP reports : innovation in hepatology
Published Date: Dec 19, 2023

Abstract

BACKGROUND & AIMS: Genetic and microbiome studies across patients with primary sclerosing cholangitis (PSC) and ulcerative colitis (UC) have indicated that UC in PSC is a separate disease entity to primary UC, but expression studies for PSC are lacking.

Authors

  • Eike Matthias Wacker
    Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, Kiel, Germany.
  • Florian Uellendahl-Werth
    Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, Kiel, Germany.
  • Saptarshi Bej
    Department of Systems Biology and Bioinformatics, Institute of Computer Science, University of Rostock, Rostock, Germany.
  • Olaf Wolkenhauer
    Department of Systems Biology and Bioinformatics, Institute of Computer Science, University of Rostock, Rostock, Germany.
  • Mette Vesterhus
    Norwegian PSC Research Center, Department of Transplantation Medicine, Division of Surgery, Inflammatory Diseases and Transplantation, Oslo University Hospital Rikshospitalet and University of Oslo, Oslo, Norway.
  • Wolfgang Lieb
    Institute of Epidemiology, Christian-Albrechts-University of Kiel, Kiel, Germany.
  • Andre Franke
    Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, Kiel, Germany.
  • Tom Hemming Karlsen
    Research Institute for Internal Medicine, Division of Surgery, Inflammatory Diseases and Transplantation, Oslo University Hospital Rikshospitalet and University of Oslo, Oslo, Norway.
  • Trine Folseraas
    Research Institute for Internal Medicine, Division of Surgery, Inflammatory Diseases and Transplantation, Oslo University Hospital Rikshospitalet and University of Oslo, Oslo, Norway.
  • David Ellinghaus
    Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, Kiel, Germany.

Keywords

No keywords available for this article.

External Resources

Popular Topics
Recent Journals