Tumor-associated microbiome features of metastatic colorectal cancer and clinical implications.

Journal: Frontiers in oncology
Published Date: Jan 18, 2024

Abstract

BACKGROUND: Colon microbiome composition contributes to the pathogenesis of colorectal cancer (CRC) and prognosis. We analyzed 16S rRNA sequencing data from tumor samples of patients with metastatic CRC and determined the clinical implications.

Authors

  • Ho Jung An
    Department of Medical Oncology, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
  • Mira A Partha
    Department of Electrical Engineering, Stanford University, Palo Alto, CA, United States.
  • HoJoon Lee
    Division of Oncology, Department of Medicine, Stanford University School of Medicine, Palo Alto, CA, United States.
  • Billy T Lau
    Division of Oncology, Department of Medicine, Stanford University School of Medicine, Palo Alto, CA, United States.
  • Dmitri S Pavlichin
    Division of Oncology, Department of Medicine, Stanford University School of Medicine, Palo Alto, CA, United States.
  • Alison Almeda
    Division of Oncology, Department of Medicine, Stanford University School of Medicine, Palo Alto, CA, United States.
  • Anna C Hooker
    Division of Oncology, Department of Medicine, Stanford University School of Medicine, Palo Alto, CA, United States.
  • Giwon Shin
    Division of Oncology, Department of Medicine, Stanford University School of Medicine, Palo Alto, CA, United States.
  • Hanlee P Ji
    Division of Oncology, Department of Medicine, Stanford University School of Medicine, Palo Alto, CA, United States.

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