Optimizing methadone dose adjustment in patients with opioid use disorder.

Journal: Frontiers in psychiatry
Published Date: Jan 8, 2024

Abstract

INTRODUCTION: Opioid use disorder is a cause for concern globally. This study aimed to optimize methadone dose adjustments using mixed modeling and machine learning.

Authors

  • Po-Shen Liu
    Department of Psychiatry, Taichung Veterans General Hospital, Taichung, Taiwan.
  • Teng-Yao Kuo
    Fundamental General Education Center, National Chinyi University of Technology, Taiping, Taiwan.
  • I-Chun Chen
    Department of Psychiatry, Taichung Veterans General Hospital, Taichung, Taiwan.
  • Shu-Wua Lee
    Department of Psychiatry, Taichung Veterans General Hospital, Taichung, Taiwan.
  • Ting-Gang Chang
    Department of Psychiatry, Taichung Veterans General Hospital, Taichung, Taiwan.
  • Hou-Liang Chen
    Tsaotun Psychiatric Center, Ministry of Health and Welfare, Nantou, Taiwan.
  • Jun-Peng Chen
    Biostatistics Task Force of Taichung Veterans General Hospital, Taichung, Taiwan.

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