Neuro-environmental interactions: a time sensitive matter.

Journal: Frontiers in computational neuroscience
Published Date:

Abstract

INTRODUCTION: The assessment of resting state (rs) neurophysiological dynamics relies on the control of sensory, perceptual, and behavioral environments to minimize variability and rule-out confounding sources of activation during testing conditions. Here, we investigated how temporally-distal environmental inputs, specifically metal exposures experienced up to several months prior to scanning, affect functional dynamics measured using rs functional magnetic resonance imaging (rs-fMRI).

Authors

  • Azzurra Invernizzi
    Department of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
  • Stefano Renzetti
    Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, Brescia, Italy.
  • Elza Rechtman
    Department of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
  • Claudia Ambrosi
    Department of Neuroscience, Neuroradiology Unit, ASST Cremona, Cremona, Italy.
  • Lorella Mascaro
    ASST Spedali Civili Hospital, Brescia, Italy.
  • Daniele Corbo
    Department of Medical Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, Brescia, Italy.
  • Roberto Gasparotti
    Department of Medical Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, Brescia, Italy.
  • Cheuk Y Tang
    Department of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
  • Donald R Smith
    Department of Microbiology and Environmental Toxicology, University of California Santa Cruz, Santa Cruz, CA, United States.
  • Roberto G Lucchini
    Department of Neuroscience, Neuroradiology Unit, ASST Cremona, Cremona, Italy.
  • Robert O Wright
    Department of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
  • Donatella Placidi
    Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, Brescia, Italy.
  • Megan K Horton
    Department of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
  • Paul Curtin
    LinusBio, Inc., New York, NY, United States.

Keywords

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