Clinical and Dosimetric Impact of 2D kV Motion Monitoring and Intervention in Liver Stereotactic Body Radiation Therapy.

Journal: Advances in radiation oncology
Published Date: Nov 23, 2023

Abstract

PURPOSE: Positional errors resulting from motion are a principal challenge across all disease sites in radiation therapy. This is particularly pertinent when treating lesions in the liver with stereotactic body radiation therapy (SBRT). To achieve dose escalation and margin reduction for liver SBRT, kV real-time imaging interventions may serve as a potential solution. In this study, we report results of a retrospective cohort of liver patients treated using real-time 2D kV-image guidance SBRT with emphasis on the impact of (1) clinical workflow, (2) treatment accuracy, and (3) tumor dose.

Authors

  • Andrew P Santoso
    Department of Radiation Oncology, University of Colorado School of Medicine, Aurora, Colorado.
  • Yevgeniy Vinogradskiy
    Department of Radiation Oncology, Thomas Jefferson University, Philadelphia, Pennsylvania.
  • Tyler P Robin
    Department of Radiation Oncology, University of Colorado School of Medicine, Aurora, Colorado.
  • Karyn A Goodman
    Department of Radiation Oncology, University of Colorado School of Medicine, Aurora, Colorado.
  • Tracey E Schefter
    Department of Radiation Oncology, University of Colorado School of Medicine, Aurora, Colorado.
  • Moyed Miften
    Department of Radiation Oncology, University of Colorado School of Medicine, Aurora, Colorado.
  • Bernard L Jones
    Department of Radiation Oncology, University of Colorado School of Medicine, Aurora, Colorado.

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