A biased coin up-and-down sequential allocation trial to determine the ED90 of intrathecal sufentanil combined with ropivacaine 2.5 mg for labor analgesia.

Journal: Frontiers in medicine
Published Date: Jan 8, 2024

Abstract

PURPOSE: To determine the 90 percent effective dose (ED90) of intrathecal sufentanil combined with ropivacaine 2.5 mg for labor analgesia and observe its safety for parturients and neonates.

Authors

  • Qiaoli Yin
    Department of Anesthesiology, General Hospital of Ningxia Medical University, Yinchuan, China.
  • Bin Yu
    Department of Anesthesiology, Peking University First Hospital, Ningxia Women's and Children's Hospital, Yinchuan, China.
  • Hua Hao
    Department of Anesthesiology, Peking University First Hospital, Ningxia Women's and Children's Hospital, Yinchuan, China.
  • Gang Li
    The Centre for Cyber Resilience and Trust, Deakin University, Australia.
  • Junyan Sun
    Department of Anesthesiology, General Hospital of Ningxia Medical University, Yinchuan, China.
  • Hao Kong
    Department of Anesthesiology, Peking University First Hospital, Beijing, China.
  • Liqin Deng
    Department of Anesthesiology, General Hospital of Ningxia Medical University, Yinchuan, China.

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