DG-GL: Differential geometry-based geometric learning of molecular datasets.

Journal: International journal for numerical methods in biomedical engineering
Published Date:

Abstract

MOTIVATION: Despite its great success in various physical modeling, differential geometry (DG) has rarely been devised as a versatile tool for analyzing large, diverse, and complex molecular and biomolecular datasets because of the limited understanding of its potential power in dimensionality reduction and its ability to encode essential chemical and biological information in differentiable manifolds.

Authors

  • Duc Duy Nguyen
    Department of Mathematics, Michigan State University, East Lansing , MI, 48824, USA.
  • Guo-Wei Wei
    Department of Mathematics, Department of Electrical and Computer Engineering, Department of Biochemistry and Molecular Biology, Michigan State University, MI 48824, USA.