Network analysis of multimorbidity and health outcomes among persons with spinal cord injury in Canada.

Journal: Frontiers in neurology
Published Date: Jan 5, 2024

Abstract

INTRODUCTION: Multimorbidity, defined as the coexistence of two or more health conditions, is common in persons with spinal cord injury (SCI). Network analysis is a powerful tool to visualize and examine the relationship within complex systems. We utilized network analysis to explore the relationship between 30 secondary health conditions (SHCs) and health outcomes in persons with traumatic (TSCI) and non-traumatic SCI (NTSCI). The study objectives were to (1) apply network models to the 2011-2012 Canadian SCI Community Survey dataset to identify key variables linking the SHCs measured by the Multimorbidity Index-30 (MMI-30) to healthcare utilization (HCU), health status, and quality of life (QoL), (2) create a short form of the MMI-30 based on network analysis, and (3) compare the network-derived MMI to the MMI-30 in persons with TSCI and NTSCI.

Authors

  • Nader Fallah
    Praxis Spinal Cord Institute, Vancouver, BC, Canada.
  • Heather A Hong
    Praxis Spinal Cord Institute, Vancouver, BC, Canada.
  • Di Wang
    Center for Endocrine Metabolism and Immune Diseases, Beijing Luhe Hospital, Capital Medical University, Beijing, People's Republic of China.
  • Suzanne Humphreys
    Praxis Spinal Cord Institute, Vancouver, BC, Canada.
  • Jessica Parsons
    Praxis Spinal Cord Institute, Vancouver, BC, Canada.
  • Kristen Walden
    Praxis Spinal Cord Institute, Vancouver, BC, Canada.
  • John Street
    International Collaboration on Repair Discoveries, University of British Columbia, Vancouver, BC, Canada.
  • Raphaele Charest-Morin
    International Collaboration on Repair Discoveries, University of British Columbia, Vancouver, BC, Canada.
  • Christiana L Cheng
    Praxis Spinal Cord Institute, Vancouver, BC, Canada.
  • Candice J Cheung
    Praxis Spinal Cord Institute, Vancouver, BC, Canada.
  • Vanessa K Noonan
    Praxis Spinal Cord Institute, Vancouver, BC, Canada.

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