Syringaresinol derived from berry attenuates oxidative stress-induced skin aging via autophagy.

Journal: Journal of ginseng research
Published Date: Aug 21, 2021

Abstract

BACKGROUND: In aged skin, reactive oxygen species (ROS) induces degradation of the extracellular matrix (ECM), leading to visible aging signs. Collagens in the ECM are cleaved by matrix metalloproteinases (MMPs). Syringaresinol (SYR), isolated from berry, has various physiological activities, including anti-inflammatory action. However, the anti-aging effects of SYR via antioxidant and autophagy regulation have not been elucidated.

Authors

  • Wooram Choi
    Department of Integrative Biotechnology, And Biomedical Institute for Convergence at SKKU (BICS), Sungkyunkwan University, Suwon, Republic of Korea.
  • Hyun Soo Kim
    Research and Innovation Center, AMOREPACIFIC, Yongin, Republic of Korea.
  • Sang Hee Park
    Department of Biocosmetics, Sungkyunkwan University, Suwon, Republic of Korea.
  • Donghyun Kim
    Research and Innovation Center, AMOREPACIFIC, Yongin, Republic of Korea.
  • Yong Deog Hong
    Research and Innovation Center, AMOREPACIFIC, Yongin, Republic of Korea.
  • Ji Hye Kim
    Department of Integrative Biotechnology, And Biomedical Institute for Convergence at SKKU (BICS), Sungkyunkwan University, Suwon, Republic of Korea.
  • Jae Youl Cho
    Department of Integrative Biotechnology, And Biomedical Institute for Convergence at SKKU (BICS), Sungkyunkwan University, Suwon, Republic of Korea.

Keywords

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