Efficacy and safety of a switch from twice-daily tacrolimus to once-daily generic tacrolimus in stable liver transplant patients.

Journal: Korean journal of transplantation
Published Date:

Abstract

BACKGROUND: Once-daily tacrolimus reduces non-compliance relative to twice-daily tacrolimus. However, little is known about the safety and efficacy of conversion from twice-daily tacrolimus to generic once-daily tacrolimus in liver transplantation (LT). Herein, we investigated the efficacy and safety of a switch from twice-daily tacrolimus to generic once-daily tacrolimus in patients with stable liver graft function.

Authors

  • Jong Man Kim
    Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
  • Pyoung-Jae Park
    Department of Surgery, Korea University College of Medicine, Seoul, Korea.
  • Geun Hong
    Department of Surgery, Ewha Woman's University School of Medicine, Seoul, Korea.
  • Dong Jin Joo
    Department of Surgery, Yonsei University College of Medicine, Seoul, Korea.
  • Kwan Woo Kim
    Department of Surgery, Dong-A University Hospital, Dong-A University College of Medicine, Busan, Korea.
  • Je Ho Ryu
    Department of Surgery, Pusan National University College of Medicine, Busan, Korea.
  • Young Seok Han
    Department of Surgery, Kyungpook National University Hospital, School of Medicine, Kyungpook National University, Daegu, Korea.
  • Jai Young Cho
    Department of Surgery, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea.
  • Gi-Won Song
    Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
  • Bong-Wan Kim
    Division of Hepatobiliary Surgery and Liver Transplantation, Department of Surgery, Ajou University School of Medicine, Suwon, Korea.
  • Dong-Sik Kim
    Department of Surgery, Korea University College of Medicine, Seoul, Korea.
  • Seong Hoon Kim
    Center for Liver Cancer, National Cancer Center, Goyang, Korea.
  • Sang Tae Choi
    Department of Surgery, Gachon University Gil Medical Center, Gachon University College of Medicine, Incheon, Korea.
  • Young Kyoung You
    Department of Surgery, College of Medicine, The Catholic University of Korea, Seoul, Korea.
  • Kyung-Suk Suh
    Department of Surgery, Seoul National University College of Medicine, Seoul, Korea.
  • Yang-Won Na
    Department of Surgery, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea.
  • Koo Jeong Kang
    Department of Surgery, Keimyung University Dongsan Hospital, Keimyung University School of Medicine, Daegu, Korea.
  • Jae-Won Joh
    Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

Keywords

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