3-Decalinoyltetramic acids from kiwi-associated fungus sp. and their antibacterial activity against .

Journal: RSC advances
Published Date: May 25, 2021

Abstract

Four rare 3-decalinoyltetramic acid derivatives, zofielliamides A-D (1-4), were obtained from cultures of kiwi-associated fungus sp. Their structures with absolute configurations were established by extensive spectroscopic methods and single crystal X-ray diffraction. The compounds possessed rare pentacyclic systems that might derive from a polyene precursor [4 + 2] intramolecular Diels-Alder reactions. Compounds 1, 2, and 4 showed antibacterial activity against plant pathogen with MIC values of 64, 32, and 64 μg mL, respectively.

Authors

  • Xue-Wen Yi
    School of Pharmacy, Anhui University of Chinese Medicine, Anhui Key Laboratory of Modern Chinese Materia Medica Hefei 230012 People's Republic of China tfeng@mail.scuec.edu.cn wanggk@ahtcm.edu.cn.
  • Juan He
    Department of Clinical Laboratory Medicine Center, Inner Mongolia Autonomous Region People's Hospital, Hohhot, Inner Mongolia, China.
  • Li-Tang Sun
    School of Pharmacy, Anhui University of Chinese Medicine, Anhui Key Laboratory of Modern Chinese Materia Medica Hefei 230012 People's Republic of China tfeng@mail.scuec.edu.cn wanggk@ahtcm.edu.cn.
  • Ji-Kai Liu
    School of Pharmaceutical Sciences, South-Central University for Nationalities Wuhan 430074 People's Republic of China.
  • Guo-Kai Wang
    School of Pharmacy, Anhui University of Chinese Medicine, Anhui Key Laboratory of Modern Chinese Materia Medica Hefei 230012 People's Republic of China tfeng@mail.scuec.edu.cn wanggk@ahtcm.edu.cn.
  • Tao Feng
    School of Pharmacy, Anhui University of Chinese Medicine, Anhui Key Laboratory of Modern Chinese Materia Medica Hefei 230012 People's Republic of China tfeng@mail.scuec.edu.cn wanggk@ahtcm.edu.cn.

Keywords

No keywords available for this article.

External Resources

Popular Topics
Recent Journals