Camurati-Engelmann Disease Complicated by Hypopituitarism: Management Challenges and Literature Review of Outcomes With Bisphosphonates.

Journal: AACE clinical case reports
Published Date: Oct 20, 2021

Abstract

BACKGROUND: Camurati-Engelmann disease (CED) is a rare bone dysplasia characterized by diffuse diaphyseal osteosclerosis. Skull base involvement in CED can result in hypopituitarism but is seldom reported. Our objective was to report a patient with acquired hypopituitarism due to CED and assess the management challenges.

Authors

  • Liza Das
    Department of Endocrinology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
  • Vandana Dhiman
    Department of Endocrinology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
  • Pinaki Dutta
    Department of Endocrinology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
  • Ashwani Sood
    Department of Nuclear Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
  • Mahesh Prakash
    Department of Radiodiagnosis, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
  • Simran Kaur
    Department of Biophysics, Panjab University, Chandigarh, India.
  • Ellen Steenackers
    Department of Medical Genetics, University of Antwerp and Antwerp University Hospital, Antwerp, Belgium.
  • Gretl Hendrickx
    Department of Medical Genetics, University of Antwerp and Antwerp University Hospital, Antwerp, Belgium.
  • Devi Dayal
    Department of Paediatrics, Division of Endocrinology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
  • Wim Van Hul
    Department of Medical Genetics, University of Antwerp and Antwerp University Hospital, Antwerp, Belgium.
  • Sanjay Kumar Bhadada
    Department of Endocrinology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

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