Analytical Quality by Design Based Systematic Development and Optimization of a Sensitive Bioanalytical Method for Estimation Cinacalcet HCl in Rabbit Serum.

Journal: Journal of pharmacy & bioallied sciences
Published Date:

Abstract

CONTEXT: There is no straightforward method for estimating cinacalcet HCl in biological materials such as serum exists. As a result, the goal of this research is to develop a simple quality by design (QbD) enabled reverse phase-Ultra-Fast Liquid Chromatography (RP-UFLC) model for analyzing cinacalcet HCl in serum.

Authors

  • Sudhanshu Bhusan Routray
    Department of Pharmaceutics, Roland Institute of Pharmaceutical Sciences, Affiliated to Biju Patnaik University of Technology, Rourkela, Odisha, India.
  • Chinam Niranjan Patra
    Department of Pharmaceutics, Roland Institute of Pharmaceutical Sciences, Affiliated to Biju Patnaik University of Technology, Rourkela, Odisha, India.
  • Suryakanta Swain
    Department of Pharmacy, School of Health Sciences, The Assam Kaziranga University, Koraikhowa, Jorhat, Assam, India.
  • Bikash Ranjan Jena
    Department of Pharmacy, School of Pharmacy and Life Sciences, Centurion University of Technology and Management, Bhubaneswar, Odisha, India.

Keywords

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