Corticosteroids and mycophenolic acid analogues in immunoglobulin A nephropathy with progressive decline in kidney function.

Journal: Clinical kidney journal
Published Date: Dec 4, 2021

Abstract

BACKGROUND: A randomized controlled trial demonstrated a beneficial effect of corticosteroids (CS) + cyclophosphamide followed by azathioprine in progressive immunoglobulin A nephropathy (IgAN). Although treatment with CS and mycophenolic acid analogues (MPAAs) remains controversial in IgAN, there is no information about their effects in progressive IgAN.

Authors

  • Ana Huerta
    Department of Nephrology, Hospital Universitario Puerta del Hierro Majadahonda, Madrid, Spain.
  • Eva Mérida
    REDInREN ISCIII 016/009, Madrid,  Spain.
  • Laura Medina
    Department of Nephrology, Hospital Universitario Infanta Leonor, Madrid, Spain.
  • Maria Fernandez
    Department of Nephrology, Hospital Universitario Doce de Octubre, Madrid, Spain.
  • Eduardo Gutierrez
    REDInREN ISCIII 016/009, Madrid,  Spain.
  • Eduardo Hernandez
    REDInREN ISCIII 016/009, Madrid,  Spain.
  • Paula López-Sánchez
    Department of Nephrology, Hospital Universitario Puerta del Hierro Majadahonda, Madrid, Spain.
  • Angel Sevillano
    REDInREN ISCIII 016/009, Madrid,  Spain.
  • Jose Portolés
    Department of Nephrology, Hospital Universitario Puerta del Hierro Majadahonda, Madrid, Spain.
  • Hernan Trimarchi
    Department of Nephrology, Hospital Británico de Buenos Aires, Buenos Aires, Argentina.
  • Manuel Praga
    REDInREN ISCIII 016/009, Madrid,  Spain.

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