Associations between depressive symptoms and disease progression in older patients with chronic kidney disease: results of the EQUAL study.

Journal: Clinical kidney journal
Published Date: Dec 16, 2021

Abstract

BACKGROUND: Depressive symptoms are associated with adverse clinical outcomes in patients with end-stage kidney disease; however, few small studies have examined this association in patients with earlier phases of chronic kidney disease (CKD). We studied associations between baseline depressive symptoms and clinical outcomes in older patients with advanced CKD and examined whether these associations differed depending on sex.

Authors

  • Boukje C Eveleens Maarse
    Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.
  • Nicholas C Chesnaye
    ERA Registry, Department of Medical Informatics, Academic Medical Center, University of Amsterdam, Amsterdam Public Health Research Institute, Amsterdam, The Netherlands.
  • Robbert Schouten
    Department of Nephrology, OLVG Hospital, Amsterdam, The Netherlands.
  • Wieneke M Michels
    Department of Internal Medicine, Leiden University Medical Center, Leiden, The Netherlands.
  • Willem Jan W Bos
    Department of Internal Medicine, Leiden University Medical Center, Leiden, The Netherlands.
  • Maciej Szymczak
    Department of Nephrology and Transplantation Medicine, Wroclaw Medical University, Wroclaw, Poland.
  • Magdalena Krajewska
    Department of Nephrology and Transplantation Medicine, Wroclaw Medical University, Wroclaw, Poland.
  • Marie Evans
    Department of Clinical Sciences Intervention and Technology, Karolinska University Hospital Huddinge, Stockholm, Sweden.
  • Olof Heimburger
    Department of Clinical Sciences Intervention and Technology, Karolinska University Hospital Huddinge, Stockholm, Sweden.
  • Fergus J Caskey
    Renal Unit, Southmead Hospital, Bristol, UK.
  • Christoph Wanner
    Department of Internal Medicine I, University Hospital Würzburg, Würzburg, Germany.
  • Kitty J Jager
    ERA Registry, Department of Medical Informatics, Academic Medical Center, University of Amsterdam, Amsterdam Public Health Research Institute, Amsterdam, The Netherlands.
  • Friedo W Dekker
    Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.
  • Yvette Meuleman
    Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.

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