Effects of two different doses of 3% hypertonic saline with mannitol during decompressive craniectomy following traumatic brain injury: A prospective, controlled study.

Journal: Journal of anaesthesiology, clinical pharmacology
Published Date:

Abstract

BACKGROUND AND AIMS: The current study was designed to compare the effects of two different doses of 3% hypertonic saline with mannitol on intraoperative events during decompressive craniectomy in traumatic brain injury (TBI). Primary outcome measures included assessment of intraoperative brain relaxation, hemodynamic variables, and serum electrolytes. Effect on the postoperative outcome, in terms of the Glasgow coma scale (GCS), length of stay in the ICU, and mortality were the secondary outcome measures.

Authors

  • Neelesh Bhatnagar
    Department of Anesthesiology and Critical Care, Geetanjali Medical College and Hospital, Udaipur, Rajasthan, India.
  • Saurabh Bhateja
    Department of Anesthesiology and Critical Care, Geetanjali Medical College and Hospital, Udaipur, Rajasthan, India.
  • Lalita Jeenger
    Department of Anesthesiology and Critical Care, Geetanjali Medical College and Hospital, Udaipur, Rajasthan, India.
  • Govind Mangal
    Department of Anesthesiology and Critical Care, Geetanjali Medical College and Hospital, Udaipur, Rajasthan, India.
  • Sunanda Gupta
    Department of Anesthesiology and Critical Care, Geetanjali Medical College and Hospital, Udaipur, Rajasthan, India.

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