Adversarial active learning for the identification of medical concepts and annotation inconsistency.

Journal: Journal of biomedical informatics
Published Date:

Abstract

OBJECTIVE: Named entity recognition (NER) is a principal task in the biomedical field and deep learning-based algorithms have been widely applied to biomedical NER. However, all of these methods that are applied to biomedical corpora use only annotated samples to maximize their performances. Thus, (1) large numbers of unannotated samples are relinquished and their values are overlooked. (2) Compared with other types of active learning (AL) algorithms, generative adversarial learning (GAN)-based AL methods have developed slowly. Furthermore, current diversity-based AL methods only compute similarities between a pair of sentences and cannot evaluate distribution similarities between groups of sentences. Annotation inconsistency is one of the significant challenges in the biomedical annotation field. Most existing methods for addressing this challenge are statistics-based or rule-based methods. (3) They require sufficient expert knowledge and complex designs. To address challenges (1), (2), and (3) simultaneously, we propose innovative algorithms.

Authors

  • Gang Yu
    The Children's Hospital, Zhejiang University School of Medicine, Hangzhou, China.
  • Yiwen Yang
    Department of Artificial Intelligence, Enterprise Institute, Ewell Technology, China. Electronic address: yangyiwen@ewell.cc.
  • Xuying Wang
    Department of Artificial Intelligence, Enterprise Institute, Ewell Technology, China. Electronic address: wangxuying@ewell.cc.
  • Huachun Zhen
    Department of Artificial Intelligence, Enterprise Institute, Ewell Technology, China. Electronic address: zhenhuachun@ewell.cc.
  • Guoping He
    Department of Artificial Intelligence, Enterprise Institute, Ewell Technology, China. Electronic address: hgp@ewell.cc.
  • Zheming Li
    Department of IT Center, the Children's Hospital, Zhejiang University School of Medicine, China; National Clinical Research Center for Child Health, China. Electronic address: 6513103@zju.edu.cn.
  • Yonggen Zhao
    Department of IT Center, the Children's Hospital, Zhejiang University School of Medicine, China; National Clinical Research Center for Child Health, China. Electronic address: 6202073@zju.edu.cn.
  • Qiang Shu
    Cardiac Surgery,Children's Hospital, Zhejiang University School of Medicine, 310052 Hangzhou, Zhejiang, China.
  • Liqi Shu
    Department of Neurology, The Warren Alpert Medical School of Brown University, Providence, RI, United States.