Photodynamic Therapy Using Toluidine Blue O (TBO) Dye as a Photosensitizer against .

Journal: Iranian journal of public health
Published Date: Oct 1, 2021

Abstract

BACKGROUND: Photodynamic therapy (PDT) is alternative treatment of cutaneous leishmaniasis (CL), and phenolthiazine dyes such as Toluidine Blue O (TBO) have the potential role in PDT and notably affect parasites inactivation. This study aimed to evaluate the effectiveness of PDT by using TBO and a light-emitting diode (LED) in the treatment of zoonotic CL (ZCL).

Authors

  • Mehdi Najm
    Department of Parasitology and Mycology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
  • Maryam Pourhajibagher
    Dental Research Center, Dentistry Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
  • Alireza Badirzadeh
    Department of Parasitology and Mycology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
  • Elham Razmjou
    Department of Parasitology and Mycology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
  • Maryam Alipour
    Department of Parasitology and Mycology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
  • Majid Khoshmirsafa
    Immunology Research Center (IRC), Iran University of Medical Sciences, Tehran, Iran.
  • Abbas Bahador
    Department of Microbiology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
  • Ramtin Hadighi
    Department of Parasitology and Mycology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.

Keywords

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