Cell death analysis of recombinant mature epsilon toxin on the kidney cell line.

Journal: Iranian journal of microbiology
Published Date: Dec 1, 2021

Abstract

BACKGROUND AND OBJECTIVES: Epsilon toxin is the third hazardous bacterial toxin causing ABS enterotoxaemia in domestic animal. In addition, epsilon toxin is known as a biological warfare agent. The aim of this study was to produce the recombinant mature epsilon toxin to evaluate cell death impact on the kidney cell line.

Authors

  • Roza Chehreara
    Department of Genetics, Faculty of Basic Sciences, Islamic Azad University, Research Branch, Tehran, Iran.
  • Shohreh Zare Karizi
    Department of Genetics and Biotechnology, School of Biological Science, Varamin-Pishva, Branch Islamic Azad University, Varamin, Iran.
  • Hamideh Mahmoodzadeh Hosseini
    Applied Microbiology Research Center, Systems Biology and Poisonings Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran.
  • Seyed Ali Mirhosseini
    Applied Microbiology Research Center, Systems Biology and Poisonings Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran.
  • Mohammad Shafiei
    Applied Microbiology Research Center, Systems Biology and Poisonings Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran.
  • Jafar Amani
    Applied Microbiology Research Center, Systems Biology and Poisonings Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran.
  • Rouhollah Kazemi
    Department of Plant Biotechnology, National Institute of Genetic Engineering and Biotechnology (NIGEB), Tehran, Iran.

Keywords

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