In Vitro Cytotoxicity and Anti-HIV Activity of Crude Extracts of , and .

Journal: Journal of experimental pharmacology
Published Date: Dec 22, 2021

Abstract

INTRODUCTION: Human immunodeficiency virus (HIV) affects the body's defense mechanisms and leads to a number of opportunistic infections which later cause fatality as a result of an acquired immunodeficiency syndrome (AIDS). More than half a million individuals have lost their life in 2020 due to this disease. Antiretroviral drugs have played a great role in improving the quality of life of HIV infected individuals. The side effects of these drugs coupled with resistance of the virus to the various regimens, necessitates the search for potentially new and effective antiretroviral medication. The objective of this study is to evaluate anti-HIV activity of crude extracts of three plants.

Authors

  • Ermias Mergia Terefe
    Department of Pharmacology and Pharmacognosy, United States International University-Africa, Nairobi, Kenya.
  • Faith Apolot Okalebo
    Department of Pharmacology and Pharmacognosy, University of Nairobi, Nairobi, Kenya.
  • Solomon Derese
    Department of Chemistry, University of Nairobi, Nairobi, Kenya.
  • Joseph Muriuki
    Centre for Virus Research, Kenya Medical Research Institute, Nairobi, Kenya.
  • Gaber El-Saber Batiha
    Department of Pharmacology and Therapeutics, Damanhour University, Damanhour, AlBeheira, 22511, Egypt.

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