QDeep: distance-based protein model quality estimation by residue-level ensemble error classifications using stacked deep residual neural networks.

Journal: Bioinformatics (Oxford, England)
Published Date:

Abstract

MOTIVATION: Protein model quality estimation, in many ways, informs protein structure prediction. Despite their tight coupling, existing model quality estimation methods do not leverage inter-residue distance information or the latest technological breakthrough in deep learning that has recently revolutionized protein structure prediction.

Authors

  • Md Hossain Shuvo
    Department of Computer Science and Software Engineering, Auburn University, Auburn, AL 36849, USA.
  • Sutanu Bhattacharya
    Department of Computer Science and Software Engineering, Auburn University, Auburn, AL 36849, USA.
  • Debswapna Bhattacharya
    Department of Electrical Engineering and Computer Science, Wichita State University, Wichita, KS, 67260, USA.