Cytoreductive radical prostatectomy after chemohormonal therapy in patients with primary metastatic prostate cancer.

Journal: Asian journal of urology
Published Date: Apr 22, 2021

Abstract

OBJECTIVE: Cytoreductive radical prostatectomy (cRP) has been proposed as local treatment option in metastatic hormone-sensitive prostate cancer (mHSPC) to prevent local complications and potentially improve oncological outcomes. In this study, we examined the feasibility of a multimodal concept with primary chemohormonal therapy followed by cRP and analyzed prostate size reduction under systemic treatment, postoperative complication rates, as well as early postoperative continence.

Authors

  • Christa Babst
    Department of Urology, Technical University of Munich, Rechts der Isar Medical Center, Munich, Germany.
  • Thomas Amiel
    Department of Urology, Technical University of Munich, Rechts der Isar Medical Center, Munich, Germany.
  • Tobias Maurer
    Martini-Klinik Prostate Cancer Center, Hamburg, Germany.
  • Sophie Knipper
    Martini-Klinik Prostate Cancer Center, Hamburg, Germany.
  • Lukas Lunger
    Department of Urology, Technical University of Munich, Rechts der Isar Medical Center, Munich, Germany.
  • Robert Tauber
    Department of Urology, Technical University of Munich, Rechts der Isar Medical Center, Munich, Germany.
  • Margitta Retz
    Department of Urology, Technical University of Munich, Rechts der Isar Medical Center, Munich, Germany.
  • Kathleen Herkommer
    Department of Urology, Technical University of Munich, Rechts der Isar Medical Center, Munich, Germany.
  • Matthias Eiber
    Department of Urology, Technical University of Munich, Rechts der Isar Medical Center, Munich, Germany.
  • Gunhild von Amsberg
    Martini-Klinik Prostate Cancer Center, Hamburg, Germany.
  • Markus Graefen
    Martini-Klinik Prostate Cancer Center, Hamburg, Germany.
  • Juergen Gschwend
    Department of Urology, Technical University of Munich, Rechts der Isar Medical Center, Munich, Germany.
  • Thomas Steuber
    Martini-Klinik Prostate Cancer Center, Hamburg, Germany.
  • Matthias Heck
    Department of Urology, Technical University of Munich, Rechts der Isar Medical Center, Munich, Germany.

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