Resection of the medial wall of the cavernous sinus in functioning pituitary adenomas: Technical note and outcomes in a matched-cohort study.

Journal: Clinical neurology and neurosurgery
Published Date: Oct 13, 2020

Abstract

BACKGROUND: Parasellar dural invasion can be associated with treatment failure after excision of functioning pituitary adenomas. Because the medial wall of the cavernous sinus is a common site of microscopic disease, we hypothesize that its resection may lead to improvement in biochemical remission and recurrence rates. We aim to describe our technique in the resection of the medial wall of the cavernous sinus using binasal endoscopic transsphenoidal surgery (BETS); and compare tumor control and biochemical remission rates against a matched cohort.

Authors

  • Abdelsimar T Omar
    Division of Neurosurgery, Department of Surgery, University of Toronto, Toronto, Ontario, Canada; Division of Neurosurgery, St Michael's Hospital, Toronto, Ontario, Canada; Neuroscience Research Program, Keenan Research Centre of the Li Ka Shing Knowledge Institute of St. Michael's Hospital, University of Toronto, Toronto, Ontario, Canada. Electronic address: atomar@up.edu.ph.
  • David G Munoz
    Department of Laboratory Medicine, Division of Pathology, St. Michael's Hospital, Toronto, Ontario, Canada.
  • Jeannette Goguen
    Department of Medicine, St. Michael's Hospital, Toronto, Ontario, Canada.
  • John M Lee
    Department of Otolaryngology, Head and Neck Surgery, St. Michael's Hospital, Toronto, Ontario, Canada.
  • Fabio Rotondo
    Department of Laboratory Medicine, Division of Pathology, St. Michael's Hospital, Toronto, Ontario, Canada.
  • Kalman Kovacs
    Department of Laboratory Medicine, Division of Pathology, St. Michael's Hospital, Toronto, Ontario, Canada.
  • Michael D Cusimano
    Division of Neurosurgery, Department of Surgery, University of Toronto, Toronto, Ontario, Canada; Division of Neurosurgery, St Michael's Hospital, Toronto, Ontario, Canada; Neuroscience Research Program, Keenan Research Centre of the Li Ka Shing Knowledge Institute of St. Michael's Hospital, University of Toronto, Toronto, Ontario, Canada. Electronic address: injuryprevention@smh.ca.

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