Renoprotective role of bariatric surgery in patients with established chronic kidney disease.

Journal: Clinical kidney journal
Published Date: Dec 23, 2020

Abstract

BACKGROUND: Bariatric surgery (BS) has been postulated as the most effective measure for weight reduction. Weight loss improves metabolic parameters and exerts changes in renal function that lead to the amelioration of absolute or relative glomerular hyperfiltration, a condition that may be renoprotective in the long term. However, few studies have demonstrated the influence of BS in patients with severe obesity and chronic kidney disease (CKD). Our objective was to analyse the evolution of renal function, adipose tissue-derived molecules and inflammatory parameters in patients with CKD after BS.

Authors

  • Enrique Morales
    Department of Nephrology, Hospital Universitario 12 de Octubre, Madrid, Spain.
  • Esteban Porrini
    Faculty of Medicine, Instituto de Tecnologías Biomédicas, University of La Laguna, Laguna, Spain.
  • Marina Martin-Taboada
    Depatment Basic Sciences of Health, Faculty of Sciences of Health, Universidad Rey Juan Carlos, Madrid, Spain.
  • Sergio Luis-Lima
    Department of Nephrology and Hypertension, IIS-Fundación Jimenez Díaz, Madrid, Spain.
  • Rocío Vila-Bedmar
    Depatment Basic Sciences of Health, Faculty of Sciences of Health, Universidad Rey Juan Carlos, Madrid, Spain.
  • Ignacio González de Pablos
    Department of Nephrology, Hospital Universitario 12 de Octubre, Madrid, Spain.
  • Pilar Gómez
    Department of Surgery, Hospital Universitario 12 de Octubre, Madrid, Spain.
  • Elías Rodríguez
    Department of Surgery, Hospital Universitario 12 de Octubre, Madrid, Spain.
  • Lucia Torres
    Depatment Basic Sciences of Health, Faculty of Sciences of Health, Universidad Rey Juan Carlos, Madrid, Spain.
  • Borja Lanzón
    Depatment Basic Sciences of Health, Faculty of Sciences of Health, Universidad Rey Juan Carlos, Madrid, Spain.
  • Ana Elena Rodríguez
    Fundación General de la ULL, Instituto de Tecnologias Biomédicas, Madrid, Spain.
  • María Maíz
    Department of Endocrinology, Hospital Universitario, 12 de Octubre, Madrid, Spain.
  • Gema Medina-Gómez
    Depatment Basic Sciences of Health, Faculty of Sciences of Health, Universidad Rey Juan Carlos, Madrid, Spain.
  • Manuel Praga
    REDInREN ISCIII 016/009, Madrid,  Spain.

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