Role of Intravenous Ascorbic Acid in the Management of Anemia in Hemodialysis Patients.

Journal: Indian journal of nephrology
Published Date: Nov 7, 2020

Abstract

INTRODUCTION: Patients with end-stage kidney disease (ESKD) suffer from functional iron deficiency where despite the presence of sufficient iron stores in the body, adequate iron is unavailable for heme synthesis. This study hypothesis was that in patients undergoing hemodialysis (HD), administration of intravenous (IV) ascorbic acid (AA) exerts a good effect on the management of anemia, either by increasing the mobilization of iron from tissue stores or acting as an antioxidant to overcome the inflammatory block and increase the erythropoietin sensitivity.

Authors

  • Howayda El Shinnawy
    Department of Nephrology, Faculty of Medicine, Ain Shams University, Egypt.
  • Abdel Rahman Khedr
    Department of Nephrology, Faculty of Medicine, Ain Shams University, Egypt.
  • Ahmad Alghitany
    Department of Nephrology, Faculty of Medicine, Ain Shams University, Egypt.
  • Marina Ramzy
    Department of Nephrology, Faculty of Medicine, Ain Shams University, Egypt.
  • Aber Halim Baki
    Department of Nephrology, Faculty of Medicine, Ain Shams University, Egypt.

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